Healing by Design

Keragel® is a thick hydrogel enriched with pharmaceutical-grade keratin protein that delivers Replicine™ Bioactive Keratin to the wound while maintaining a moisture-rich environment. Keragel® is indicated for acute/chronic superficial and partial thickness wounds with dry-to-medium exudate, such as1:

  • Venous leg ulcers
  • Arterial ulcers
  • Diabetic ulcers
  • Pressure ulcers
  • Skin graft donor sites
  • First and second degree burns and sunburns

Improved Wound Healing

Keragel® has demonstrated faster epithelialization rates and more robust skin after healing in numerous clinical studies. This means Keragel® can speed healing, improve the healed outcome, and reduce cost of care in the following treatment areas2-5:

  • Chronic Wound Care
  • Scar Management
  • Burn Treatment
  • Skin Tears

See our Clinical Data

See Prescribing Information here.





No adverse events have been reported. Available in 20gm tube, NDC 71474-301-20 1.  Cleanse and debride the wound in accordance with normal procedures.
2. Ensure that the skin surrounding the wound is dry.
3. To open the tube, use the piercer cap to break the nozzle seal. To ensure sterility, sanitize the piercer cap before use.
4. Apply a 3mm to 6mm (1/8inch to 1/4inch) layer of Keragel® to cover the entire wound surface.
5. Cover with an appropriate secondary dressing if needed.


The wound should be inspected daily or as indicated by a physician. For wounds that appear dry, more gel should be applied to the area. Wounds should be cleansed regularly and new gel applied.


1.Keragel® [package insert.] Molecular Biologicals: Pasadena, TX; 2017. 2.Batzer AT, Marsh C, Kirsner RS. The use of keratin-based wound products on refractory wounds. Int Wound J. 2016;13(1):110-115. 3.Davidson A, Jina NH, Marsh C, et al. Do functional keratin dressings accelerate epithelialization in human partial thickness wounds? A randomized controlled trial on skin graft donor sites. Eplasty. 2013;3:375-381. 4.Loan F, Cassidy S, Marsh C, et al. Keratin-based products for effective wound care management in superficial and partial thickness burns injuries. Science Direct. 2016;42:54-547. 5.Pechter PM, Gil J, Valdes J, et al. Keratin dressings speed epithelialization of deep partial-thickness wounds. Wound Rep Reg. 2012;20:236-242. 6.Denyer J, Marsh C, Kirsner RS. Keratin gel in the management of Epidermolysis bullosa. J Wound Care. 2015;24(10):446-450.