Reimbursement/Resources

Keramatrix®


To order Keramatrix®, call 1-844-793-9933. Hours of operation: 8am – 5pm CST.


Covered Sites of Service:
Physician Office, Hospital Outpatient Department, & Ambulatory Surgery Center


Download the full reimbursement guide.


Q4165: Skin Substitute, KERAMATRIX®, per square centimeter
Modifier – JC*: Skin substitute used as graft
Modifier – JW*: Drug amount discarded/not administered to any patient
Modifier – KX*: Requirements in the medical policy have been met **This modifier may also apply to application code**
CPT 15275: Application of skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area up to 100 sq cm; first 25 sq cm or less wound surface area
CPT 15276: Each additional 25 sq cm wound surface area, or part thereof (list separately in addition to code for primary procedure)
CPT 15277: Application of skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; first 100 sq cm wound surface area, or 1% of body area of infants and children
CPT 15278: Application of skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; first 100 sq cm wound surface area, or 1% of body area of infants and children

Units Billed

Check units billed – Keramatrix® is a single-use product – CMS and private payers generally reimburse for the entire piece, even where it is reasonable and necessary to discard a portion.

**Check your Local Coverage Determination (LCD) for additional billing information



Product Wastage Documentation Requirements

Any amount of wasted material should be clearly documented in the medical record with the following information:

  1. Date, time, and location of ulcer treated
  2. Approximate amount of product unit used
  3. Approximate amount of product unit discarded
  4. Reason for the wastage
  5. Manufacturer’s serial/lot/batch or other unit identification number of graft material


Modifiers

Check to see if modifiers are required with HCPCS Q4165 – common modifiers include:

*JC – skin substitute used as a graft
*JW – wastage
*KX – requirements in the medical policy have been met.

Check to see if modifiers are required with CPT 15275.



Wound Size

When determining the wound location and surface area, it is important to select the appropriate CPT code.

Ulcer(s) less than 100 sq cm: Utilize CPT 15275 and the add-on code of 15276 as necessary.

Ulcer(s) greater than or equal to 100 sq cm: Utilize CPT 15277 and the add-on code of 15278 as necessary.



Debridement

Debridement is considered a component code of 15275/15277.



Diagnosis Codes Order

Check the LCD or private payer policy to ensure diagnoses are in the proper order.



Commercial Insurers Contract

Check your payer contracts prior to applying Keramatrix® coding and coverage is not a guarantee of payment.

CPT is a registered trademark of the American Medical Association. The listed CPT codes apply to all skin substitute products.

It is at the provider’s discretion to decide when Keramatrix® is a medical necessity. Molecular Biologicals will not solicit the use of Keramatrix® outside of FDA-cleared indications. See prescribing information here.
Molecular Biological cannot guarantee reimbursement. It is the provider’s responsibility to determine the appropriate utilization of products and services along with the appropriate coding.

To order Keramatrix®, call 1-844-793-9933. Hours of operation: 8am – 5pm CST.